Caliskan Lab is seeking highly motivated postdoctoral fellows to illuminate dynamics of RNA molecules and their interplay with other factors during translational recoding events and transcription using state of the art single-molecule analysis and imaging tools. In this regard, we are especially interested in hiring candidates with proven expertise in single-nucleotide and single-molecule analysis of RNA complexes, transcription or translation (Pekarek et al., Nucleic Acids Research, 2024, Kibe et al., Nature Struct. Mol. Biol. 2025).

Job Qualifications:

• Ph.D. or equivalent in biochemistry, molecular biology, biophysics or a related field of the life sciences or engineering.
• Solid understanding of RNA biology, transcription and translation mechanisms.
• Experience in single molecule techniques (SM-FRET or optical tweezers).
• Experience with R, Python or MatLab for high-throughput data and image analysis.
• Excellent communication skills in English (German is a plus, but not mandatory)
• Strong publication record given career stage
• High motivation to contribute to an international and innovative workplace, problem solving and good organizational skills

Location:

Germany, Regensburg

Regensburg is a Medieval city in Baveria with a 2,000-year-old history and UNESCO World Heritage status, named as one of the top destinations in Central Europe. Here is some more information on culture and life in Regensburg.

The University of Regensburg, founded in 1962, has developed into a renowned center for RNA research in Germany with a strong tradition in international cooperation. Furthermore, with its twelve faculties, it has a broad variety of disciplines with excellent individual research, innovative, inter- and multidisciplinary research projects and an attractive quality-assured range of courses.

About us:

Caliskan Lab is fascinated with the RNA molecules that alter the triplet periodicity of the genetic code and how proteins impact the way an mRNA is being translated under stress conditions and infection. Key areas of our work include the analysis of structure and function of RNA molecules and RNA-protein complexes regulating translation and the fate of an RNA in the cell. To exploit RNA-based gene regulatory events, we employ a highly interdisciplinary and cutting-edge biochemical, molecular biology, and structural biology techniques, combining single-molecule fluorescence, optical tweezers and next-generation sequencing methods (Pekarek et al., Nucleic Acids Research, 2024; Kibe et al., Nature Struct. Mol. Biol. 2025; Zimmer and Kibe et al, Nature Comm. 2021; Hill, Pekarek et al., Nature Comm. 2021). Furthermore, we make use of a range of model organisms and purified systems, from bacteria and yeast to insects and human cells.

Through our research, we aim to gain new insights that not only deepen our understanding of RNA-based gene regulation but also pave the way for potential applications in medicine.

If that sounds interesting, please also visit our website to learn more about our other projects and our young and dynamic team. 

Benefits:

• Be part of a high-impact research that will shape the future to create new RNA antiviral drugs and immunotherapies.
• Access to state-of-the-art facilities and resources, for example: C-Trap.
• Competitive Salary. Remuneration group TV-L E13
• A full-time, fixed term or permanent position (depending on experience and funding).
• A highly collaborative, interdisciplinary and inclusive work environment.
• Many possibilities to develop independence and gain new skills.
• Support to apply for external third-party funding.
• Assistance with relocation and integration into Germany, if applicable.
• We offer 30 days of paid annual vacations.
• Opportunity to have long term employment and habilitation.

We welcome applications from all backgrounds. The promotion of diversity is an important goal for us, we promote equal opportunities.

Start date: 

Start date is as soon as possible and the minimum duration of the employment is 2 years. 

Application Deadline:

2025-06-30. Applications will be considered as they are received, until all positions are filled.

How to Apply:

If this vacancy sounds like a good fit for you, we’d love to hear from you!

Please send us your application a single PDF file including:

▪    Your CV

▪    A short cover letter telling us why you're interested in this role.

▪    Copies of your degrees or certificates.

▪    Reference letters or contact details of 2-3 referees. 

▪    Any other documents that show your skills and experience.

Feel free to reach out to Prof. Caliskan ([email protected]) if you have any questions!