Stuart Lab at Seattle Children’s Research Institute is seeking a Postdoctoral Scientist (Fellow) with interests in molecular mechanisms of RNA processing in Trypanosomatid pathogens. The project focuses on the functions of essential multiprotein complexes that perform the guide RNA directed post-transcriptional RNA editing that generates functional mRNAs in Trypanosomes, which controls the composition and function of cellular energy systems in different Trypanosome parasite life cycle stages. The project will use a combination of complementary genetic, molecular, cellular, protein structure/function, and informatic methods. It will determine how the catalytic and non-catalytic components of multiprotein complexes interact with each other and the mRNA and gRNA substrates to post-transcriptionally generate functional mRNAs and do so differentially between developmental stages.

The successful candidate will have a strong interest in cellular and molecular biology, especially with respect to protozoan pathogens, and expertise in basic cell and molecular biological techniques.  Strong written and verbal communication skills, the abilities to establish clear goals, organize and prioritize research, work with a diverse team of scientists, and thrive within a multi-disciplinary environment are critical.

Interested applicants should provide a cover letter detailing their scientific achievements, goals, and a description of their interest, in addition to a curriculum vitae that indicates their education, experience, and qualifications. A Ph.D. or equivalent biomedical degree in cell and molecular biology and/or microbiology, experience in molecular analyses and a strong understanding of cellular processes are required.

The research is conducted in the highly interactive Seattle research environment that includes the closely located University of Washington School of Medicine, Seattle Children’s Research Institute and Fred Hutchinson Cancer Research Center.

Send expression of interest and CV to: [email protected]