Fully Funded PhD Opportunity (Open to Both UK and International Candidates) at Lancaster University, UKNovember 12, 2024 About the Project The PhD project focuses on RNA modification enzymes, which "typeset" RNA molecules and play crucial roles in immune system regulation—positioning them as promising targets for innovative therapies. As part of this research, you will gain hands-on experience with cutting-edge technologies, including RNAomics (tools for analyzing RNA molecule dynamics within cells) and advanced biomolecular 3D imaging, enhanced by computational methods and artificial intelligence. These state-of-the-art techniques will allow you to uncover critical molecular insights into how RNA modification enzymes influence immune function and health. Throughout your PhD, you will receive comprehensive support and training in both established and emerging research techniques, ensuring that you are future-proofed for the evolving landscape of biomedical research in both academia and industry. Your work will have the potential for high-impact applications in heart disease, cancer, and other immune-associated human diseases. If you are inspired by cutting-edge breakthroughs in science and excited to develop a unique, competitive skill set within a supportive, diverse, and inclusive research environment, apply now to join our mission! You will benefit from a tailored career development plan and close collaboration between two vibrant and UK Research & Innovation-funded research laboratories at Lancaster University (Aikaterini Gatsiou Lab) and the University of Glasgow (Helen Walden Lab), with a strong track record and commitment to mentoring PhD students. Lancaster University and the University of Glasgow are both ranked among the top institutions globally for biomedical research The successful candidate will be based at Lancaster University, ranked among the top 3 UK institutions for Biomedical Science andinthe top 10 UK institutions overall, and will join the Department of Biomedical & Life Sciences, which has recognised expertise in immunity, cancer research, and molecular genetics. The Department is supported by state-of-the-art research facilities and works closely with Lancaster’s world-leading Data Science Institute, a key partner of the World Health Organization, utilizing artificial intelligence and machine learning tools for data analysis and biomolecular research. About the City of Lancaster Lancaster is a historic city in the North West of the UK, blending rich heritage with a vibrant student life. Home to the iconic Lancaster Castle and two prestigious universities, it offers direct access to both the Lake District and the Yorkshire Dales—two world-renowned National Parks celebrated for their outstanding natural beauty and outdoor activities. Additionally, Lancaster boasts award-winning sandy beaches along its coastline, offering excellent opportunities for water-based activities. With easy access to Manchester Airport and regular direct train services to London, Lancaster is well-connected, while also offering the charm of independent cafes, cultural festivals, and scenic canal walks. Combining history, nature, and modern living, Lancaster provides a unique and welcoming environment. About the Application Process Closing Date for Full Application: Monday, 6th of January, 2025 Basic salary: According to UK 2024/25 rate; Duration: 4 years If you are interested in this exciting opportunity, please reach out well in advance to: Dr. Aikaterini Gatsiou at [email protected] Informal discussions about the specifics of the project or the full application process are highly encouraged. Please ensure that you attach your CV/Resume to the email when you reach out. Before reaching out, please ensure that you meet the eligibility requirements and have the necessary supporting documentation available. References 1. Gatsiou, A., et al. The RNA editor ADAR2 promotes immune cell trafficking |