RNA Society E-Jobs

Position available in Dept of Ecology and Evolutionary Biology of the University of Kansas, Lawrence, United States

Thu, 02 Sep 2010 12:49:48 GMT

An NSF funded postdoctoral position is available in the laboratory of Justin Blumenstiel at the University of Kansas to study the evolution and function of trans-generational silencing by small RNA. The primary focus of the project is to elucidate the mechanisms by which different classes of silencing RNA inherited through the female germline (piRNA and endo-siRNA) maintain silencing of transposable elements across generations. A second major focus of the lab is the study of the co-evolutionary dynamics of genome defense by germline silencing. Research in the lab joins genetic, molecular and evolutionary approaches. The proposed project will take a joint approach that includes small RNA analysis using next gen sequencing and cytological analysis of germline development in Drosophila virilis. The integrative nature of research in the laboratory make this position ideal for a molecular biologist interested in taking evolutionary approaches or an evolutionary biologist interested in pursuing a mechanistic understanding of genome defense by small RNA. Start date is flexible. Qualifications: Competitive applicants will be driven by interest in either epigenetics or evolution and have a strong background in molecular biology or genetics. Experience in any of the following would be a plus: Drosophila genetics, microscopy and immunofluorescence and the analysis of high throughput sequencing data using a programming language such as Perl or Python. Applicants should submit a CV, a letter of research interests and the contact information for three references to Justin Blumenstiel: jblumens[at]ku.edu

Position available in Department of Chemistry & Biochemistry of the University of Bern, Bern, Switzerland

Tue, 13 Jul 2010 18:59:23 GMT

Full Professor in Biochemistry The Department of Chemistry and Biochemistry of the University of Bern, Switzerland, invites applications for a full professorship in biochemistry. Research at the department (www.dcb.unibe.ch) is focused on the molecular foundations of biological processes and includes nucleic acids. Candidates should demonstrate exceptional potential to develop an innovative research program in RNA biochemistry (e.g. processing/function/dynamics/RNA-protein interactions) and be willing to cooperate within and outside the University of Bern. The candidate is expected to contribute to the undergraduate and graduate teaching curricula in protein biochemistry and biophysical methods for students of biochemistry, chemistry and biology. The University of Bern is an equal opportunity employer and strives to increase the number of women in the faculty. Qualified female researchers are especially encouraged to apply. The position is to be filled by August 1, 2011, the deadline for applications is August 31, 2010. Interested candidates should submit their curriculum vitae, a synopsis of their past, current and proposed research, a list of publications, indicating the 5 most relevant papers, an outline of their teaching experiences and the completed questionnaire (to download at: www.dcb.unibe.ch/content/departement/offene_stellen/) as a single PDF file or as a hard copy to: Prof. Urs Feller Dean Faculty of Science University of Bern Sidlerstrasse 5, CH-3012 Bern, Switzerland e-mail: dekan[at]natdek.unibe.ch Informal inquiries may be addressed to: Prof. André Schneider, phone + 41 (0)31 631 4253 e-mail: andre.schneider[at]ibc.unibe.ch

Position available in Dept. of Research of the New England Biolabs Inc., Ipswich, United States

Tue, 13 Jul 2010 18:56:04 GMT

New England Biolabs is actively seeking a full-time Research Associate in the RNA Biology Division to start immediately. This position will assist with discovery and development focused research projects. Projects will be a part of a basic research program into gene regulation mediated by small regulatory RNA pathways. Research will be undertaken in a highly collaborative and academic-style environment where publication of results is a top priority. The candidate will work on projects related to: · Small RNA isolation, identification, characterization, and manipulation using enzymatic, biochemical, and high-throughput techniques. · RNA-protein complex identification and characterization using chromatographic purification, electrophoresis, and mass spectrometric analysis. · Functional characterization of ribonucleoprotein complexes including cloning and over expression, and in vitro reconstitution. The ideal candidate will have: · Proven bench skills in RNA analysis, protein analysis and standard molecular biology techniques. · Experience with protein expression and purification. · A strong work ethic, emphasizing both efficiency and quality of work. · The ability to multi-task effectively while working independently, and/or contributing to team goals. · Excellent written and verbal communication skills. · A commitment to research excellence, strong analytical skills, and enthusiasm to learn and develop new techniques. Qualifications: · Advanced degree in molecular biology, biochemistry, or other related fields. New England Biolabs, Inc. is an equal opportunity employer M/F/D/V

Position available in Dept of Biochemistry and Biophysics of the University of Rochester, Rochester, United States

Tue, 13 Jul 2010 18:54:36 GMT

A postdoctoral position is available in the laboratory of Dmitri Ermolenko at the Department of Biochemistry and Biophysics & Center for RNA Biology, School of Medicine and Dentistry, University of Rochester to begin August 2010 or as negotiated. We are seeking talented and motivated postdoctoral fellow to study mechanism of bacterial and eukaryotic translation. We use ensemble and single molecule fluorescence resonance energy transfer to study structural dynamics of the ribosome and translation factors. Applicants must have a recent Ph.D. and expertise in molecular biology with publications in international peer-reviewed journals. Applicants with experience in ribosome and RNA biochemistry and/or fluorescent spectroscopy are encouraged to apply. Please submit a statement of research interests and experience, and current curriculum vitae to Dmitri Ermolenko at Dmitri_Ermolenko[at]URMC.Rochester.edu.

Position available in Dept of Ecology and Evolutionary Biology of the Princeton University, Princeton, United States

Mon, 07 Jun 2010 12:30:32 GMT

Postdoctoral Research Associate or senior research position in the Department of Ecology and Evolutionary Biology at Princeton University, with focus on DNA Rearrangements, Recombination, Epigenetics, Evolution, and non-coding RNAs in the unicellular eukaryote Oxytricha. Professor Laura Landweber seeks a postdoctoral research associate to study the mechanism of scrambled gene and genome rearrangements in ciliates, particularly the role of non-coding RNAs or epigenetic factors, using experimental or bioinformatic research tools or both. Requirements: PhD in molecular biology or relevant field. Strong experimental or computational training, experience, and publications from the PhD, ability to work independently and creatively, and strong research and written/oral communication skills are necessary. For more information about the lab, see http://www.princeton.edu/~lfl and recent publications, such as Nature 2008, v451, p153 (http://www.ncbi.nlm.nih.gov/pubmed/18046331) or Science 2009, v324, p935 (http://www.ncbi.nlm.nih.gov/pubmed/19372392). This is initially a one-year appointment with possibility of renewal based on satisfactory performance. Funding is currently available for three years. Apply online at http://jobs.princeton.edu/. Search for Requisition # 1000366 and include a letter, CV, statement of research interest, and email addresses of three references. Application review will begin immediately; start date is flexible. Princeton University is an equal opportunity employer and complies with applicable EEO and affirmative action regulations

Position available in PGD, NICHD of the NIH, Bethesda, Bethesda, United States

Mon, 17 May 2010 05:44:54 GMT

Postdoctoral Fellowship Position Eukaryotic RNA Metabolism National Institutes of Health (NIH), Bethesda, Maryland The Fellow will investigate molecular mechanisms involved in RNA metabolism, and this may include links between transcription, RNA processing, nuclear transport, and translation. Fission yeast as well as mammalian cell culture serve as a model genetics systems, and efforts may include massively parallel whole genome sequencing for mutant mapping. We also use biochemistry, mammalian tissue culture, and genetically altered mice. Laboratory approaches integrate cell biology, molecular biology, genetics, biochemistry and structural biology. The applicant should email a cover letter that details his/her specific interest in the research areas described above and as reflected by the publications from the Maraia lab. Candidates must hold a Ph.D. or M.D. and have less than 5 years postdoctoral experience. Expertise in molecular biology, genetics and/or biochemistry is required, as are strong letters of recommendation. The successful candidate will confer regularly with the principal investigator but must incorporate self-directed research, as well as excellent technical, presentation, and communication skills as essential parts of the job. Position to start Oct 1, 2010 with duration of appointment up to 5 years contingent on annual performance evaluation. Send your cover letter, C.V., and the names of three references with their email addresses and telephone numbers by Email to: Richard J. Maraia, M.D. Email: maraiar[at]mail.nih.gov 31 Center Dr., Room 2A25 Bethesda, MD 20892-2426

Position available in Dept. of Cellular and Molecular Pharmacology of the Chicago Medical School, Rosalind Franklin University, North Chicago, United States

Mon, 17 May 2010 05:41:47 GMT

A Department of Defense-funded Research Associate/Research Technician position is available immediately in the laboratory of Dr. Judith Potashkin at the Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, to study biomarkers for Parkinson’s disease. We are looking for a highly motivated scientist experienced in working with RNA who will conduct experiments to identify a splice isoform biosignature for Parkinson’s disease. For more information visit our lab website. Requirements: A BS or BA degree in molecular biology, biochemistry or related field is required. Preferred applicants will have experience in working with RNA, qPCR analysis and bioinformatics. Location: The Chicago Medical School at Rosalind Franklin University of Medicine and Science is located twenty miles north of downtown Chicago with convenient train access to the city. The University provides a diverse, multidisciplinary, and collaborative research environment. Application: Candidates should submit by e-mail a (1) CV and (2) a cover letter that includes an approximate date when you would be available to start to: Dr. Judith Potashkin Chicago Medical School, Rosalind Franklin University Dept. of Cellular and Molecular Pharmacology 3333 Green Bay Rd. North Chicago, IL 60064 judy.potashkin[at]rosalindfranklin.edu.

Position available in Center for Anatomy & Cell Biology of the Medical University of Vienna, Vienna, Austria

Mon, 10 May 2010 07:08:14 GMT

A postdoctoral position to study a presumptive role of mitochondrial tRNA maturation in the pathogenesis of Alzheimer’s disease is available in the lab of Walter Rossmanith at the Medical University of Vienna. The project originates from the recent identification of the components of human mitochondrial RNase P and is embedded in the group’s broad interest in mitochondrial tRNA biology in health and disease. The project is funded by a grant from the Agouron Institute. Eligible candidates should hold a PhD in molecular biology, biochemistry, or related field. They should have documented experience in RNA biology and/or enzymology. The position is available now and funded for one year. Please submit a statement of research experience and interests, a CV including list of publications, names and contact details of three references, as well as a minimum of one reference letter. Address applications to walter.rossmanith[at]meduniwien.ac.at

Position available in Dept of Molecular Tools Lab of the Agilent Laboratories, Santa Clara, United States

Sat, 01 May 2010 19:26:13 GMT

R&D Scientist, RNA Sciences, Agilent Laboratories, Santa Clara, CA Agilent Laboratories, Agilent Technologies’ central research laboratories in Santa Clara, CA is seeking a Scientist for the Molecular Tools Lab to actively pursue life sciences research as part of an innovative multidisciplinary team developing novel RNA measurement technologies. The successful candidate will identify and pursue advancements in RNA measurement technology that will have a tangible impact on advancing the next generation of biological research in key areas such as cancer, neurological diseases, cardiovascular disease, stem cell research and synthetic biology. The candidate will join a team working to invent, develop and test new methods for the next generation of Agilent platforms and establish and lead strategic collaborations between Agilent Labs and external researchers to validate and proliferate these novel methods. For example, conduct applied research into developing new methodologies for profiling RNAs using microarrays as well as other emerging technologies and for characterizing structural and functional properties of non-coding and coding RNAs. In the course of developing new applications, evaluate opportunities for creating new data analysis and visualization tools in order to provide an integrated solution for acquiring and reducing data and representing complex biological information in collaboration with Agilent Labs computational biology and informatics experts. Communicate progress and results to management and technical leadership, to selected external organizations and, when appropriate, to the general scientific community via presentations at scientific conferences and peer-reviewed publications. REQUIRED QUALIFICATIONS: • Ph.D. in Biochemistry, Physical Chemistry, Molecular Biology, Biology, Chemistry or other relevant field plus minimum 2-3 years post-doctoral experience (academic or industrial) or equivalent. • Demonstrated forefront achievements in life sciences research as evidenced, for example, by high profile peer-reviewed publications, patents or invited talks. • Demonstrated expertise in enzymology associated with nucleic acid manipulation and measurement. • Expertise in physical chemistry of nucleic acids, especially as relevant to RNA manipulation and measurement. • Hands-on experience with RNA measurement technologies, e.g. DNA microarrays, sequencing, and related methods. • Demonstrated success and direct responsibility for developing and/or utilizing new or emerging technologies for RNA profiling and/or functional characterization of different classes of RNAs. • Demonstrated leadership in initiating and pursuing successful collaborative research projects with interdisciplinary and inter-institutional teams. • Strong problem solving and quantitative data analysis expertise. • Excellent communication, teamwork and leadership skills. DESIRED QUALIFICATIONS: • Experience analyzing large data sets and using bioinformatics tools. • Experience with in silico and experimental tools for determining RNA structure. • Experience studying RNA-Protein interactions. We invite you to please visit www.jobs.agilent.com and apply directly to requisition 2033207. Candidate must have work authorization.

Position available in Department of Cell Biology of the Lerner Research Institute, Cleveland Clinic, Cleveland, United States

Sat, 01 May 2010 19:21:01 GMT

A Postdoctoral Fellow position is available in the laboratory of Donna Driscoll to study the mechanism and regulation of selenoprotein synthesis (Mol. Cell, 35:479, 2009; RNA Biology, 6:73, 2009; J. Biol. Chem. 282:34653, 2007; Nature Str. Mol. Biol,12: 408, 2005). Selenoproteins are a small but important group of proteins that play a variety of roles in human health and disease. The translation of selenoprotein mRNAs involves the recoding of the UGA stop codon as selenocysteine, the 21st amino acid. The goals of our research are to characterize the trans-acting factors that are required for this novel recoding event, identify functionally important RNA structures and RNA-protein interactions, and elucidate regulatory pathways that control selenoprotein expression during selenium deficiency. More information about our research program can be found at http://www.lerner.ccf.org/cellbio/driscoll/. We are seeking highly motivated, independent, creative, and enthusiastic individuals who have excellent oral and written communication skills. A Ph.D. in biochemistry, chemistry, molecular biology or a related discipline is required. Students who are finishing their Ph.D. degree and recent graduates are encouraged to apply. The ideal candidate will have expertise in RNA biology or translational control, but applicants with strong training in molecular biology, nucleic acid biochemistry, or protein biochemistry will be seriously considered. The position is available as of July 1, 2010 but the start date is flexible. The initial appointment is for one year and is extendable, depending on mutual agreement as per institute policy. The Department of Cell Biology is a vibrant and diverse department, with over 20 faculty members (http://www.lerner.ccf.org/cellbio/). The Lerner Research Institute provides an excellent environment for biomedical research, with state-of-the-art facilities and competitive salaries and benefits. Our Research Education Office provides continuing support for career development. For information on our postdoctoral training program, see http://www.lerner.ccf.org/education/postdoc/. Applicants will also have the opportunity to interact with the extensive RNA community within the institute and at nearby Case Western Reserve University. As an equal opportunity and affirmative action employer, the Cleveland Clinic recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives, and backgrounds. To apply, please email a CV, a brief description of research interests and career goals, and the names and contact information for three references to Dr. Donna Driscoll (driscod[at]ccf.org).