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Position available in Department of Molecular biology of the Swedish University of Agricultural Sciences (SLU) , Uppsala, Sweden
Position posted on Saturday, June 28, 2008
A post-doc position is available in the RNA Biology Group at the Department of
Molecular Biology/Swedish University of Agricultural Sciences (SLU). The aim of the
research is to further understand the function of small RNAs, i.e. microRNAs (miRNAs)
and small interfering (siRNAs) and their associated proteins during growth and
development. The genetically tractable social amoeba Dictyostelium discoideum is used
as a model for these studies. Dictyostelium is a well-established model organism for
studies of different developmental processes. It is also of interest from an evolutionary
perspective, branching out after plants but before the animal/fungi lineages and
positioned in the interface between uni- and multicellularity.
We have recently identified a large number of small RNAs in Dictyostelium and
demonstrated that their biogenesis is dependent on different RNA interference related
genes (Hinas et al, 2007, NAR). We are now entering the next exciting phase – to
understand their function during growth and development! This will be analyzed using a
number of different biochemical, molecular, and cell biological tools, e.g. targeted gene
disruptions, isolation of protein-RNA complexes, localization studies using in situ and
gene-fusion techniques.
You will be part of the Linneaus/Swedish Research Council supported center of
excellence (URRC - Uppsala RNA Research Center) where ten research groups at
Uppsala University and SLU, situated at the Biomedical Center (BMC), study different
aspects of RNA biology.
The applicant should hold a PhD and have a strong background in molecular biology.
Experience in RNA research, e.g. RNA-protein interaction and mi/siRNA studies is a
great advantage. You must be able to work independently but also interact/collaborate
with group members and collaborators. Strong written and oral English communication
skills are required. The projects involves national and international collaborations.
The application must include your CV, list of publications, previous research
accomplishments (1 page) and names and contact information of at least two academic
references.
The position is for up to two years.
Contact :
Dr Fredrik Söderbom
Tel :
Fax :
Email : fredde[at]xray.bmc.uu.se
Position available in Intramural Program on Genomics of Differentiation, NICHD of the NIH, USA , Bethesda, United States
Position posted on Saturday, June 28, 2008
The Fellow will investigate molecular mechanisms involved in RNA metabolism,
including links between transcription, RNA processing and nuclear transport. A major
focus of the laboratory is RNA polymerase III and the La protein. Fission yeast serve as
a model system to study human as well as yeast La protein function. We also use
mammalian tissue culture and genetically altered mice. Laboratory approaches integrate
cell biology, molecular biology, genetics, biochemistry and structural biology.
Candidates must hold a Ph.D. and have less than 5 years postdoctoral experience.
Expertise in molecular biology, genetics and/or biochemistry is required, as are strong
letters of personal recommendation. The successful candidate will confer regularly with
the principal investigator but must incorporate self-directed research, excellent technical,
presentation, and communication skills as essential parts of the job. As an applicant, you
should submit a cover letter that details your specific interest in the specific research
areas described above and as reflected by the publications from the Maraia lab. A
PubMed search link of these publications can be found on the URL listed below.
Send your cover letter, C.V., and the names of three references with their email addresses
and telephone numbers by Email to:
Richard J. Maraia, M.D.
Email: maraiar[at]mail.nih.gov
31 Center Dr., Room 2A25
Bethesda, MD 20892-2426
Contact :
Dr Rich Maraia
Tel : 301 402-3567
Fax :
Email : maraiar[at]mail.nih.gov
Position available in Dept of Biochemistry & Molecular Biology of the Uniformed Services University of the Health Sciences (USUHS) , Bethesda, United States
Position posted on Saturday, May 24, 2008
An NIH-funded post-doctoral position is available immediately in the laboratory of Dr. Tharun Sundaresan [Assistant Professor, Department of Biochemistry and Molecular Biology, Uniformed Services University of the Health Sciences (USUHS), Bethesda, MD, USA] to study the role of Sm-like proteins in mRNA turnover in the yeast S. cerevisiae. Relevant publications are (GENETICS 2005; 170:33-46) and (RNA 2007; 13:998-1016). Eligible candidates should have a Ph.D in biochemistry, molecular biology or a related discipline. Experience in protein purification, RNA work and yeast molecular biology will be an advantage. Salary will depend on experience. Send curriculum vitae and 3 references to Dr. Tharun Sundaresan (tsundaresan[at]usuhs.mil).
Contact :
Dr Tharun Sundaresan
Tel : 301-295-9423
Fax : 301-295-3512
Email : tsundaresan[at]usuhs.mil
Position available in Wellcome Trust Centre for Cell Biology of the University of Edinburgh , Edinburgh, Scotland
Position posted on Saturday, May 24, 2008
Following recent successes of group members in obtaining faculty positions, we invite applications from final year graduate students and postdoctoral researchers. Applicants should have a PhD and at least one first author paper in a good international journal (or expect to obtain these in the immediate future). We would also consider applications from researchers without a PhD but with substantial relevant expertise. Available from July 2008 onwards for three years.
We are particularly interested in recruiting new researchers to work on:
1) The links between non-coding RNA transcripts and chromatin structure.
2) The application of systems biology techniques to modeling ribosome synthesis.
3) Characterization of the binding sites and functions of ribosome synthesis factors using RNA-protein cross-linking.
For further details visit: http://homepages.ed.ac.uk/dtoller/
Contact :
Dr David Tollervey
Tel : +44 131 650 7092
Fax : +44 131 650 7040
Email : d.tollervey[at]ed.ac.uk
Position available in Dept of Pathology, Molecular & Cellular Biology of the Baylor College of Medicine , Houston, United States
Position posted on Saturday, May 24, 2008
RNAs have rapidly emerged as the key players in many fundamental biological processes, as well as the bridge to future medicine. The research goals of our laboratory are to harness the power of RNA to create new therapeutic instruments for biomedical studies. Our current research areas include (1) the development of RNA-based molecular switches that can be turned on or off by small molecules for gene regulation, (2) RNA-based cellular biosensors for detecting specific intracellular molecules in disease, and (3) the identification of cancer-specific splice isoforms as biomarkers for cancer diagnosis and therapy. We are particularly interested in applying these technologies and knowledge in the fields of cancer, stem cell, and diabetes. Please see link (http://www.bcm.edu/pathology/labs/yen/index.htm) for details.
We seek a postdoctoral fellow with strong research skills to join our lab at Baylor College of Medicine. Individuals with a Ph.D. and experience in molecular or RNA biology are encouraged to apply. Baylor College of Medicine is a world-renowned research institution located in the heart of the Texas Medical Center. Ample opportunities exist for scientific interactions with neighboring institutes such as MD Anderson Cancer Center, Rice University, University of Texas Health Center, and many research hospitals. The breadth and quality of biomedical science in the Texas Medical Center rivals that of any biomedical research center in the world. Our lab interacts regularly with several other labs in the Texas Medical Center including monthly joint lab meetings and a biweekly RNA journal club. If you are interested in RNA, and enjoy solving scientific puzzles, please send email to:
Laising Yen, Ph.D.
Assistant Professor
Department of Pathology
Department of Molecular & Cellular Biology
Baylor College of Medicine
yen[at]bcm.edu
Contact :
Dr Yen Laising
Tel :
Fax :
Email : yen[at]bcm.edu
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